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Prologue M. Teresa Anguera Basic aspects and research 1. Is addiction a chronic relapsing disease? Martien Kooyman 2. In it for the long haul: recovery capital, addiction theory and the inter-generational transmission of addictive behaviour Rowdy Yates 3. Self-Medication and addictions Miquel Casas 4. Promoting Best Practice in the drug addiction fi eld: the EMCDDA experience Marica Ferri 5. Chronobiology and addiction: implications for treatment and prevention Ana Adan Sex differences 6. Biological bases of sex diff erences in drug addiction Marta Torrens 7. Female polydrug abuse and psychopathology - Gender diff erences: an overview Edle Ravndal 8. The impact of motherhood on recovery - Lessons we can learn from the treatment journeys of mothers with problematic substance misuse issues Karen Biggs Therapeutic communities 9. Quality of life in therapeutic communities for substance abuse Eric Broekaert 10. The essential elements of treatment: a European therapeutic communities perspective Ilse Goethals 11. MECETT, the journeymen model transferred to staff training in TCs George van der Straten 12. The reasons for the rise and fall of the Bremberg empire Vera Segraeus Social and politic factors 13. The United Nations and drug demand reduction policies Xavier Fernández-Pons 14. Factors for eff ective long-term recovery: risk and challenges during the economic crisis in Greece Charalampos Poulopoulos 15. Getting regular, early and brief alcohol interventions into primary care in rural New South Wales: the origins of the Murdi Paaki Drug and Alcohol Network Rod MacQueen 16. Social exclusion and immigration: new patterns of drug use among young marginal migrants Núria Empez 17. Politics and ethics for a journal editor Richard Pates Conclusions Conrad Vilanou